It is difficult to determine exactly how long it will take for your immune system to become stronger once you stop taking methotrexate, as it varies from person to person. Factors such as age, duration of taking methotrexate, and overall physical health can influence this timeframe, which can range from weeks to months. However, it is important to note that despite being considered at higher risk due to being immunosuppressed, your risk of contracting COVID-19 is not significantly higher than that of the general population. This is because the virus is new and there is currently no effective defense for the population as a whole. Ultimately, it is recommended that you discuss your specific situation with your healthcare provider to make the best decision for your health.