There is no specific contraindication to taking CBD oil with your current medication regimen. However, it is important to be aware that it may cause you to feel a bit sedated, especially since you are already taking Trintellix. Additionally, there could be a decrease in the effectiveness of Vyvanse, especially if the oil is consumed during the day rather than at night. If you experience any strange feelings or unwanted effects, it is recommended to stop taking the oil immediately.