Antidepressants like Zoloft can help reduce anxiety, but they may not completely eliminate it. It is normal to still experience some level of anxiety in daily life. The effectiveness of an antidepressant may take several weeks to fully kick in, and sometimes adjustments to the dosage may be needed. It is important to work closely with your doctor to find the right treatment plan for you and to improve your quality of life. Remember, managing anxiety is about finding ways to cope with different situations rather than expecting it to disappear completely.