There may be other medications or combinations of medications that could be more effective than Prevacid for severe GERD. It is important to speak with a pharmacist or healthcare provider to explore different options if necessary. Additionally, if the maximum dose of Prevacid has been reached and there has been little to no improvement after 4 weeks of treatment, it may be time to consider alternative treatments. A healthcare professional can evaluate the situation and suggest alternative medications or combinations as needed.