There is no known interaction between Trintellix and Xanax. However, when it comes to breastfeeding, it is important to be cautious as Xanax can pass into breast milk and potentially impact the child. It is advisable to discuss this with your doctor to assess the risks versus benefits. Your doctor may consider switching to a similar medication with a shorter duration of action to minimize exposure to the child. If you have any further questions, feel free to reach out for more information.