Medimap Logo

Is there an interaction between Zoloft and alcohol? If so, can one drink moderately while being treated with 50mg per day?

Yes, there is an interaction between Zoloft and alcohol. Both substances are depressants of the nervous system, meaning they can decrease certain brain mechanisms that help keep us awake. Taking them together could lead to a more pronounced decrease in alertness. It is advisable to drink alcohol in moderation and be aware of any increased effects due to the medication.