Yes, there are over-the-counter medications that you can take to help with inflammation and pain in the salivary gland during pregnancy. Acetaminophen is a safe option for pain relief at any trimester. If you are in your second trimester, you may also consider taking Advil/Motrin, but it is recommended to use it sparingly. It is always best to consult with your pharmacist for a more detailed response based on your individual circumstances such as other medications or allergies.