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Is there any contraindication to receiving the COVID-19 vaccine if I have the MTHFR gene mutation?

There is no known contraindication to receiving the COVID-19 vaccine if you have the MTHFR gene mutation. In fact, some studies suggest that certain variations of this mutation may increase vulnerability to COVID-19 infection. The only current contraindication to the vaccine is if you have had an anaphylactic reaction to one of its components.