There is no significant interaction between citalopram and fluconazole when fluconazole is taken as a single dose for treating vaginitis. However, if fluconazole is taken daily for several weeks for certain types of infections, there is a potential risk of interaction that could affect the liver and increase citalopram concentrations. This risk is almost nonexistent when taking just one dose. Similarly, moderate alcohol consumption is generally not contraindicated with a single dose of fluconazole.
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