Yes, there are several over-the-counter products that can help with intense itching on the hands. It is recommended to visit your local pharmacy and consult with a pharmacist who can evaluate your hands and recommend the most appropriate treatment. Typically, a combination of a cortisone cream and a fragrance-free moisturizing cream is used to treat this type of dermatitis. The moisturizing cream should be applied in large quantities several times per day. It is important to avoid scratching, as this can worsen inflammation by disrupting the skin barrier. If you experience itching, applying a cold damp towel can help reduce the sensation. Avoid using irritating products on the skin, such as household cleaners, dish soap, or heat, and consider wearing gloves when necessary. To promote skin hydration during the night, you may also consider wearing cotton gloves after applying your moisturizer before bedtime.