Trintellix 10mg is generally considered better than Cipralex 20mg for reducing weight gain, excessive sweating, and hot flashes. Trintellix is less likely to cause weight gain compared to Cipralex, and it is also less known for causing excessive sweating and hot flashes. It is important to note that side effects can vary between individuals, so it's essential to find the medication that works best for you. Nausea may occur, especially in the first few days of treatment, but this typically improves with time. It is recommended to gradually increase the dose to help manage this side effect.