If you are experiencing a sore throat and a lot of coughing with mucus buildup in your throat, it is recommended to use saline nasal irrigation to help prevent the mucus from dripping down the back of your throat, which can often cause coughing. This can be done with products like Hydrasense or Sinus Rinse multiple times a day and at least 30 minutes before bedtime. While it may be slightly uncomfortable, it can be very effective in relieving symptoms.